[HTML][HTML] Effect of bortezomib on global gene expression in PC12-derived nerve cells

K Łuczkowska, D Rogińska, Z Ulańczyk… - International Journal of …, 2020 - mdpi.com
… influence of bortezomib on PC12-derived nerve cells, we carried out GSEA to identify altered
pathways in bortezomib-treated PC12-derived nerve cells vs. control cells. According to the …

Peripheral neuropathy in patients with multiple myeloma: molecular effects of bortezomib

K Łuczkowska, B Machaliński - Acta Haematologica Polonica, 2021 - journals.viamedica.pl
… miRNA and target genes in neuronal cells differentiated from PC12 cells was the decreased
Effect of bortezomib on global gene expression in PC12-derived nerve cells. Int J Mol Sci. …

[HTML][HTML] Bortezomib-induced epigenetic alterations in nerve cells: focus on the mechanisms contributing to the peripheral neuropathy development

K Łuczkowska, D Rogińska, P Kulig… - International Journal of …, 2022 - mdpi.com
PC12-derived nerve cells to BTZ leads to alterations in the miRNA expression in genes
responsible for cell … for disturbances in gene expression and signaling pathways in nerve cells. …

Paeoniflorin ameliorates BiPN by reducing IL6 levels and regulating PARKIN-mediated mitochondrial autophagy

R Sun, J Liu, M Yu, M Xia, Y Zhang, X Sun… - Drug Design …, 2023 - Taylor & Francis
… Citation57 PC12 cells are derived from rat pheochromocytoma cells and are … effects of
bortezomib on PC12-derived neuronal cells. After bortezomib treatment, the activity of PC12 cells

[HTML][HTML] The Potential Role of Proinflammatory Cytokines and Complement Components in the Development of Drug-Induced Neuropathy in Patients with Multiple …

K Łuczkowska, M Rutka, D Rogińska… - Journal of Clinical …, 2021 - mdpi.com
… (bortezomib, thalidomide, dexamethasone) regimen, in the present study, we examined global
mRNA expression … A direct toxic effect of IFN-γ on nerve cells has been demonstrated. IFN-…

microRNAs as the biomarkers of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma

K Łuczkowska, D Rogińska, Z Ulańczyk… - Leukemia & …, 2021 - Taylor & Francis
Global miRNA expression profile in the plasma of patients … Like the vast majority of
drugs, bortezomib and thalidomide … The relative gene expression was quantified using the …

[HTML][HTML] Comparative analysis of global gene expression and complement components levels in umbilical cord blood from preterm and term neonates: Implications for …

D Gródecka-Szwajkiewicz, Z Ulańczyk… - International Journal …, 2020 - ncbi.nlm.nih.gov
… We aimed to investigate global gene expression and the levels of several complement …
them to term newborns. We sought to examine how differentially expressed genes could affect …

[HTML][HTML] Local and systemic humoral response to autologous lineage-negative cells intrathecal administration in ALS patients

B Baumert, A Sobuś, M Gołąb-Janowska… - International Journal of …, 2020 - mdpi.com
… regulation of processes associated with neuronal cells survival and function, … gene expression
changes after transplantation of lineage-negative cells with particular emphasis on genes

[HTML][HTML] … angiopoietic factors and expression of microRNA in umbilical cord blood from healthy appropriate-for-gestational-age preterm and term newborns—in search …

D Gródecka-Szwajkiewicz, Z Ulańczyk… - International Journal of …, 2020 - mdpi.com
… of gene expression with gene silencing by miRNA and in the negative regulation of cell
may be a manifestation of immaturity of neuronal cell population throughout the whole body […

miR-152-3p aggravates vascular endothelial cell dysfunction by targeting DEAD-box helicase 6 (DDX6) under hypoxia

Z Zhao, C Wu, X He, E Zhao, S Hu, Y Han, T Wang… - …, 2021 - Taylor & Francis
… in PC12-Derived nerve cells [… DDX6 expression was downregulated in HUVECs under
hypoxia. MiR-152-3p inhibition upregulated mRNA expression and protein levels of DDX6 in cells